The USP Apparatus 1 (rotating basket), typically used to assess drug product reproducibility and evaluate oral solid dosage forms performance, consists of a cylindrical glass vessel with a. DOI: 10. Phishing. 3. Uses: Container. Berikut ini adalah soal dan jawaban tentang sepakbola pilihan ganda. The most common basket rotation speed is 100 rpm (87 methods of 122). 1985. 1N HCl and 2% SLS. Baskets were rotated at 100 rpm with USP Apparatus 1 and different flow rates from 16−32 mL/min with USP Apparatus 4 were used. Methods: Dissolution profiles were obtained with the USP basket and paddle apparatus at 50, 75, and 100 rpm and 900 ml of water as dissolution medium. Instead, Pipcorn is a great case of a brand using specificity to carve out their own unique place in the market, choosing instead to focus on what makes their product a smart choice for the health-conscious or vegan consumer. L’équipe de France U16F est championne d’Europe. Essayez dès maintenant l'application gratuite Score'n'co. The basket also features a small flap to prevent the tablet escaping during testing. Research Scientist with demonstrated experience Process Development and Tech Transfers in… | Learn more about Andres Martinez, PhD's work experience, education, connections & more by visiting. Domain Blacklisting Status. Results of aspirin release from four PEG bases prepared in this laboratory are presented and. x Abstract The difference between BP and USP rotating basket. A dissolution experiment evaluates the rate and extent that a compound forms a solution. Available in many different mesh sizes and USP compliant. Which is more officers than the 639 officers the NPS, has for decades claimed is sufficient for safe and effective USPP operations. Dissolution baskets should be perfectly round, not deformed, with the correct and verified mesh size. EP2 269 585A2 2 5 10 15 20 25 30 35 40 45 50 55 Description [0001] This application claims benefit of U. Pharmacopeia (USP) Dissolution Apparatus 1 and 2 to help assure that critical. Acetylsalicylic acid (ASA) was studied as a pure drug substance and as three simple tablet compositions with microcrystalline cellulose (MCC) and/or lactose as excipients. A dosage unit is placed in a dry basket at the beginning of each test. 8 Thus the Lord God showed me [a vision], and behold, there was a basket of [overripe] summer fruit. 5555 Baltimore City 1. 5. Shafts are standard electropolished, but also avaialble with different types of coatings. The qualification process for ensuring that a paddle or basket apparatus is suitable for its intended use is a highly debated and controversial topic. The mission of the United States Park Police is to support and further the goals of the Department of Interior and the National Park Service by providing quality law enforcement, safeguarding lives, protecting our national treasures and symbols of democracy, and preserving the natural and cultural resources entrusted to us. 3. Origin: Conrad-Pyle Company, West Grove, PA by D. The United States Basketball. Elles commencent le samedi 5 septembre et se poursuivent les samedis 12, 19 et 26 septembre ! pour plus d'informations, cliquez ici. Seniors 1F - R3;. € 171,29 € 214,11. Or use the RS to retrieve sinkers from the vessels after a USP 2 paddle method. S. The USP Apparatus 1 (basket apparatus) is commonly used to evaluate the dissolution performance of oral solid dosage forms. 5 µm) thick may be used. Aujourd'hui l'USP Basket vous présente sa nouvelle identité visuelle. USP Basket - Saint Pierre de BressieuxUnited States Park Police. , rotation speed, temperature control, etc. USP creates and continuously revises USP–NF standards through a unique public–private collaborative process, which involves pharmaceutical scientists in industry, academia, and government as well as other interested parties from anywhere in the world. 384 likes · 48 talking about this · 9 were here. 1016/j. And I said, “A basket of summer fruit. For media with a pH of 6. Results of aspirin release from four PEG bases prepared in this laboratory are presented and discussed. 9−5. 1 pouches were used as test products. Apparatus 7 can use volumes as low as 25mL with a standard Apparatus, and even as low as 3mL with the modified Apparatus 7 (400-DS from Agilent). The most common basket rotation speed is 100 rpm (87 methods of 122). USPP: Upper San Pedro Partnership (Sierra Vista, AZ) USPP: United States Pathway. A dosage unit is placed in a dry basket at the begin-creatin can be added to produce not more than 1750 USPning of each test. Forty-four niacin formulations were examined by the United States Pharmacopeia dissolution test, consisting of 0. Results of aspirin release from four PEG bases prepared in this laboratory are presented and discussed. 850-DS 8-Channel Filter Plate 0. campionati milano - lega acsi basket life. shop has landed on any online directories' blacklists and earned a suspicious tag. Basket (Apparatus 1)—Basket dimensions must conform to <711> Dissolution, Figure 1. 2. Create new account. Type 3 Reciprocating cylinder 6-35rpm CR, chewable tablets. top-uspp. com : U. This variety's more upright habit makes it great for hedging. USP-NF. • Misdemeanors committed in the presence of USPR, SA or USPP that present an immediate threat to the h ealth and safety of the public. Supplier: Quality Lab Accessories. USP apparatus 1 - 40 mesh dissolution basket for Pharmatest dissolution baths. Statements. Download scientific diagram | Statistical comparisons summary for basket and paddle method. If your USPP lapses, product upgrades are then charged at 75% of the purchase price. 0 to 2. This guidance is intended to aid drug manufacturers (including ancillary testing laboratories) in calibrating U. Basket method is very simple, robust, and easily standardized. 2 mm; oblate; firm; picking scar small; medium-dark; ripens ∼6 mo. 800. MORE. Start Now. The f2 and f1 values were ≤39. 2019. Japanese Pharmacopeia Basket Sinker. 20 mesh basket. 5 µm) thick may be per 1000 mL. pour suivre les résultats , voici le. Kinetics showed a great variability when the USP Apparatus 1 was used, and Gompertz fitted well. The use of automatic detection using modified disks is permitted where the use of disks is specified or allowed. 07) is compatible with current versions of the following key Normally, for basket and paddle apparatus, the volume of the dissolution medium is 500 mL to 1000 mL, with 900 mL as the most common volume. Bienvenue sur la page officielle de l'UST Basket, Equeurdreville. The volume can be raised to between 2 and 4 L, using larger vessels and depending on the concentration and sink conditions of the drug; justification for this procedure is expected. These tools are not official and do not affect the interpretation of the USP-NF, FCC, or any other USP-developed compendium. Nere and Russell. Dissolution testing. USP–NF is a combination of two compendia, the United States Pharmacopeia (USP) and the. 634 likes · 1 talking about this. Seniors 3G - DM3; Seniors 4G - DM5; Seniors 5G - DM5; Detentes Filles; JEUNES; BABY BASKET / MULTISPORTS; PLANNING MATCH. A Increasing the bid for the keywords you are targeting. Ornamental cultivar suitable for hanging baskets. Spring clips on clip style basket shafts. The price will automatically reflect based on the usage in your cart. Superior disease resistance and tolerance to summer heat. fr. Tennis de table. The basket and paddle apparatus are well established and broadly used for the assessment of in vitro dissolution of solid oral dosage forms. The Force functions as a unit of the National Park Service with jurisdiction in all Federal parks. Simulations with a high viscosity fluid (1 Pa-s) showed a 10-fold increase in shear stress on a tablet but a decrease in strain rate compared to low-viscosity medium (0. USAP Basket TV est la chaine YouTube du club de basket d'Avignon - Le Pontet. Category: Distek Baskets. The USP Apparatus 1 (basket apparatus) is commonly used to evaluate the dissolution performance of oral solid dosage forms. Park Police officers are located in the Washington, DC, New York City, and San Francisco metropolitan areas. USP Basket - Saint Pierre de Bressieux, Saint-Pierre-de-Bressieux. Prune lightly in the early spring (February or March), just above the first pair of new swollen leaf buds, removing about 12 inches from each shoot. Fruit: large, average 2. DissolutionAccessories. shop the absolute lowest rank on the platform: 0. . [29] is very simple, robust, and easily standardized. ; The simplest. Tolerates summer heat better in partial shade and when given adequate moisture. The USP basket Both the USP Apparatus 1 and 2 share some common advantages method is the method of choice for dissolution testing of immediate- and disadvantages. It aims to facilitate the recognition of pharmacopoeial dissolution test procedures by regulatory authorities in the ICH regions. Premium quality 6" long by 9" diameter leaf canister that fits in-line between two 1-1/2. <br> <br>. Seniors 3G - DM3; Seniors 4G - DM5; Seniors 5G - DM5; Detentes Filles; JEUNES; BABY BASKET / MULTISPORTS; PLANNING MATCH. Information. It is usually referred to as a rotating basket because it rotates smoothly and its rotating speed must be in form with the recommended USP. Beasiswa ini berupa pembebasan 100% USPP selama 1 semester Waktu Pengajuan dan Pengumuman : Waktu. USPP "Ensemble pour gagner" Union Sportive le Pin-en-Mauges la Poitevinière. HOME ORGANIZERstudies were conducted using USP basket method. Primary Material - Seagrass. and 37. 2 cm in diameter and 5 to 7 mm in thickness, with six holes, each 22 to 26 mm in. The hydrodynamics generated by the basket contributes, in general, to. Peperomia angulata – Beetle Peperomia (4. Create your website today. Here,. the disintegration and dissolution standards for dietary supplements Basket-Rack Assembly—The basket-rack assembly consists ofUSP Method 1 - Rotating Basket. C. . 5 % and 96. ” Then the Lord said to me, “The end has come for My people Israel. , and other internationally harmonized Pharmacopeia as well as in. At higher basket speeds, the predicted velocities at the center of the basket were closer to in vivo predictions but the surface shear stress was about 2 orders of magnitude lesser. Made with premium quality material ensuring it's longevity and durability. The apparatus consists of a metallic drive shaft connected to the cylindrical basket. “Il basket è l'unico sport che tende al cielo". The hydrodynamics generated by the basket contributes, in general, to the dissolution rate and hence the dissolution results. Dissolution testing measures the extent and rate of solution formation from a dosage form, such as tablet, capsule, ointment, etc. Different basket mesh sizes can be selected to ensure the most discriminatory method between formulations. Carpenter. The leaf canister. Berruyer Némoz charpente. Push smash. Drug samples were taken and quantified during 60 min by UV analysis at 260 nm. Disintegration Basket Di-200. GARDES DE SALLES; RENCONTRES; PHOTOS/VIDEOS. 3 The values stated in SI units are to be. . Plant Beetle Peperomia in a container or hanging basket as a houseplant or use as a summer patio plant. The hydrodynamics generated by the basket contributes, in general, to. (a) Physical images of the vessel and 10-mesh basket used to build 3D bodies and for visual experiments. Antigout Agents (Non-renal Tubular Blocking Agents and Non-xanthine Inhibitors) Hormonal Agents, Stimulant/ Replacement/ Modifying (Adrenal)Home Delivery Number - 8880077745. The focus of the study was to develop discriminatory dissolution methods for portioned snus and moist snuff sub-categories of smokeless tobacco products (STPs) using USP basket and paddle apparatuses. 8 or greater, pan-used. Shafts are standard electropolished, but also avaialble with different types of coatings. 1% by paddle and basket methods, respectively. The durable solid clear canister body allows you to see at a glance when the filter basket requires emptying. At higher basket speeds, the predicted velocities at the center of the basket were closer to in vivo predictions but the surface shear stress was about 2 orders of magnitude lesser. Interpretation. Avis à tous les licenciés du club et à tous ses sympathisants, rejoignez le groupe US Ploeren Basket ! Bienvenue dans le club de basket le + sympa du Morbihan, où la bonne humeur est. The basket mesh cylinder should be at right angles to the plane of the bottom and top rings. L'Union Sportive La Poitevinière/ Le Pin en Mauges est un club. 25 cm long and having an inside diameter of 20. ; GRAY, v. Adopted in 1970 the rotating basket method of dissolution testing was the first official method. Mart{\'i}nez and Kushal Sinha and Nandkishor K. Visitation increased 41% in the National Park Service. PVT is a holistic test and by using the reference standard material and the standard procedure, laboratories can compare results from their instrument with other laboratories worldwide. The modular RS robotic station can easily be added to your fully automated dissolution system ATF Xtend™. Notre projet continue, c'est pourquoi nous sommes fiers de vous dévoiler notre nouveau logo. Reciprocating disc 1. The faster release was observed for suppositories A and B with modified basket method, however slower release of paracetamol was observed for suppositories C and D (Figure 3). All basket shafts are laser marked with a unique serial number. A higher stirring speed may be justified by high variability of the results (e. Masonry Contractor. Officers 1 and 2 attended initial civilEvaluating the dissolution performance of two metronidazole generic products and the reference product Flagyl® at two doses under the hydrodynamic environment generated by the flow-through cell and to compare it with the results obtained with the USP official basket method found significant differences. The oldest. It reflects varied progress and suggests that some goals will not be realized by their 2025 target. US Avignon Pontet Basket, Avignon. Drug samples were taken and quantified during 60 min by UV. 1016/j. 008 Corpus ID: 208186735; Characterization of the Hydrodynamics in the USP Basket Apparatus using Computational Fluid Dynamics. Overview Different in sizes, this three-piece multi-utility basket set will offer an elegant decor touch. For any questions about the PDG and its processes,. 925. Pemain dalam sebuah tim bola voli yang bertindak sebagai pemain bertahan dan posisinya di daerah belakang, dan tidak berhak melakukan pukulan serangan servis ,block, maupun usaha memblock disebut. Even a slight The basket geometry and mesh size significantly influence the hydrodynamics and resultant drug dissolution profile in rotating basket dissolution testing. USP Apparatus 4 with laminar flow at 24 ml/min and 0. S. The Agilent reciprocating holder apparatus (USP Apparatus 7) is ideal for automatic dissolution testing of dosage forms requiring a change of media, smaller volume or more vigorous agitation. If Chief Chambers estimate is off by 50%, the number of officers needed by the USPP is 700. 0, USP, March 22, 2010. The f 2 value between paddle at 50 rpm versus basket at 100 rpm for PEO-based tablet was 44, while under the same conditions for HPMC-based tablets it was 63. . USP 26 compliant felodipine suspended basket for Erweka dissolution testers. 5–64. May 13, 2017 · USP Basket - Saint Pierre de Bressieux. Page officielle du Comité de BasketBall du Maine-et-Loire 6 rue Pierre de Coubertin, 49137 Les Ponts-de-Cé, FranceThe <711> Dissolution General Chapter will be incorporated into and become official with the Second Supplement to USP 34–NF 29. The rpm values of Apparatus 1 (basket) vary in the range of 35–200 rpm. Bienvenue à l'USPP. The paper is organized by contemporary dissolution topics. doi: 10. Use it to keep your pool clean and ready for use. HelloAsso est une entreprise sociale et solidaire, qui fournit gratuitement ses technologies de paiement à l'organisme US PONT SAINT MARTIN BASKET . The USP Performance Verification Test (PVT) is an integral part of the General Chapter <711> Dissolution and assesses proper dissolution apparatus performance. Rue Rodolphe Vadet, Pavilly, France. (f) Body mesh of a quarter of the 3D volume used for empty, not tablet conditions and for TC simulations. Shafts are standard electropolished, but also avaialble with different types of coatings. As of May 1, 2023. Sunbasket’s healthy meal delivery focuses on high-quality and mostly organic ingredients, meats, fish and produce in easy-to-cook recipes, many of which are designed specifically for various diets and dietary restrictions. Nos U11 Fille évoluent en championnat départemental, l'équipe est dirigée par Gabin. The effect of sampling cannula on dissolution testing attracted the attention of FDA scientists in early 1980s. General Chapter, 〈711〉 Dissolution. Rockville, MD: United States Pharmacopeia. -Once a year (but analysts are asked to check with every use), baskets are examined for being straight - no deformation. Media should be aqueous buffer solutions adjusted to pH values between 1. - Galettes des rois - 老 En tant que sponsor du club de basket USPP le magasin de la Poitevinière à décidé de reverser 1€ pour l'achat de chaque galette. tall (15-22 cm) and 24-36 in. Accessories. The Quick Latch™, or self-splicing bars that come pre-installed on wire basket tray systems. Sedikit mirip dengan soal yang memberikan jawaban metode pilihan ganda, hanya ada sedikit perbedaan dari konsepnya. 1002/jps. The USP basket method is the method of choice for dissolution testing of immediate-The basket is located within a gray-volume which is the moving reference frame (MRF). DOI: 10. Entrez le nom de votre club favori ou de votre ville. The hydrodynamics generated by the basket contributes, in general, to the dissolution rate and hence the dissolution results. In USP Apparatus 1, 250-mg products. U. Key facts about the USPP market • The USPP market is well established, existing for more than three decades. The dosage form is inserted through the opening in the top of the basket and the cover is inserted horizontally in the basket to keep it in the lower portion of Dissolution is the process in which a substance forms a solution. Ploeren. scribed, add a disk. 5 °C by using a USP basket dissolution apparatus. Brazelton and A. Dissolution baskets should be perfectly round, not deformed, with the correct and verified mesh size. The United States Park Police ( USPP) is the oldest uniformed federal law enforcement agency in the United States. Fasilitas beasiswa yang diterima : Mendapatkan beasiswa berupa pembebasan Uang Sumbangan Masuk (USM). QC方法用于药品研发. Add to cart. Question 15: Local directories are a great tool for getting noticed locally online. @article{Martnez2019CharacterizationOT, title={Characterization of the Hydrodynamics in the USP Basket Apparatus using Computational Fluid Dynamics. Découvrir les solutions clubs. Contours of velocity magnitude (m/second) from CFD simulations of a) the paddle apparatus at 50 rpm; b) the basket apparatus at 100 rpm; and c) 12 mm flow-through cell, 17 mL/min, at 0. Share in the comments your experience. Men's Basketball vs Voorhees November 25, 2023 4:00 p. Dissolution testing. RSD were less than 20% at all points of dissolution profiles, and dissolution plateau were achieved in 30 min at some of the tested conditions. A basket having a gold coating of about 0. Double Delight® Primrose Begonia tuberhybrida 'Kerbespicup' USPP 32,638, Can. Shafts are standard electropolished, but also avaialble with different types of coatings. To be considered eligible, applicants must meet the minimum qualifications, which are as follows: Be a United States citizen. Keep win USP. Nature's Basket is an online supermarket & premium grocery store offering the best online food & international grocery shopping experience in India at best prices. Any changes introduced by different basket geometries can potentially and significantly impact the system hydrodynamics and cause variability of. Simulations with a high viscosity fluid (1 Pa-s) showed a 10-fold increase in shear stress on a tablet but a decrease in strain rate compared to low-viscosity. All our baskets are laser marked with a unique serial number and come with a Certificate of Conformance. Read the article Potential Application of USP Paddle and Basket Dissolution Methods in. Faire un liveHigher stirring speeds or different basket mesh sizes may be applied with an appropriate justification. Perform a complete USP 1 method automatically from placement basket handling to a streamlined post-test cleaning routine. 7707-3700. 5 min and DE of 25. . S. Nov. of suppositories A and B containing 250 of paracetamol from modified basket. Then the Lord said to me, “The end has come for My people Israel. Related Pages. Performs well towards the front of a border, also excellent for massing or in mixed containers, hanging baskets and window boxes. We use a unique fabrication process. Quick smash. 4. USPP | La Poitevinière USPP. ‼️ ÉVÈNEMENT ‼️. [1]tubes of the basket and, if the tablet has a soluble externalevidence of disintegration, cracking, or softening. 00. As a result, the basket creates a small radial flow that impacts the vessel wall forming two loops that recirculate the flow in order for the primary radial flow to feed itself and exist in the first place since the vessel is a closed system. Issuance can be broad based, with non-U. FIP Position Paper on Qualification of Paddle and Basket Dissolution Apparatus, AAPS PharmSciTech 16 July,. Étape suivante. Scam Detector gives top-uspp. 0%). tb05020. 850-DS 8-Channel Filter Plate 0. Page officielle du club USP Basket, suivez-nous en favoris pour ne rien rater de la vie du Club !dosage-filled baskets for testing. , to predict in vivo drug release profiles. Also remove any dead or weak stems at the. 8% Poor dissolution was found in both dissolution mediums when USP basket method was used (< 10% dissolved) while better results were obtained with USP Apparatus 4 when 1% SLS at 24 mL/min was used. The rpm values of Apparatus 1 (basket) vary in the range of 35–200 rpm. Dissolution Toolkit Procedures for Mechanical Calibration and Performance Verification Test, Ver. USPP#22684: unlicensed propagation prohibited. , 1, 3, 5, 10, 15, 30, 45 min) from a prescribed location within the vessel. PSBSK150-PT 150 mesh Stainless steel Basket, supported with 20 mesh – PSBSK200-PT 200 mesh Stainless steel Basket, supported with 20 mesh – PSBSKSUP-PT Suppository Basket, Plastic 311-3000-6 PSBSK010-PTG 10 Mesh Stainless Steel Basket, Gold coated – Pharmatest PSBSK010-PTG PSBSK010-ST PSBSK020-ST PSBSK040-ST PSBSK400. Unless testing USP or other monograph then follow the test method. There is no appreciable horizontal motion or movement of the axis This general chapter is provided to determine compliance withfrom the vertical. Each holster listed above is able to be handmade for the H&K USP 9mm. Here, the hydrodynamics of Apparatus 1 was quantif. 3–92. e. 1 and ≤43. , to assess batch-to-batch consistency of solid oral dosage forms such as tablets, and drug development, i. USP. . It functions as a full-service law enforcement agency with responsibilities and jurisdiction in those National Park Service areas primarily located in the Washington, D. BASKET SHAFTS The rotating basket assembly is individually serialized with the serial number laser imprinted on the shaft for record keeping purposes. 0001 inch (2. }, author={Andr{'e}s F. My product passes 80% in 10 minutes and 100% in 20 minutes using USP basket at 100rpm. Créez votre site aujourd'hui. At higher velocities, the relationship between the intrinsic dissolution rate constant and linear velocity was parabolic rather than linear. This term divulges whether top-uspp. The USP basket method is the method of choice for dissolution testing of immediate- Dimensions of basket apparatus and CFD mesh. The formulations (2 ml) were loaded in dialysis tubes (see Section 2. Simulations with a high viscosity fluid (1 Pa-s) showed a 10-fold increase in shear stress on a tablet but a decrease in strain rate compared to low-viscosity. BASKET SHAFTS The rotating basket assembly is individually serialized with the serial number laser imprinted on the shaft for record keeping purposes. • While typically unrated, USPP debt is generally considered comparable to investment grade public corporateUSPP = United States Plant Patent. Computational fluid dynamics (CFD) has been extensively used for the USP paddle apparatus II, but limited CFD studies have been conducted on the USP basket apparatus I. Résultats FFBB: Ici. John’s Church last June, but instead did so to allow a. 💻. Complementary resources. Sur un même écran, on peut suivre l'équipe de ses enfants ou des clubs pros comme les Metropolitans de Boulogne ou le SIG Strasbourg. 1016/j. 1 percent. This is vital as the USPP has for some time lacked sufficient on-duty officers to respond effectively to critical incidents. Reciprocating cylinder 4. i. 25 mm width allowing for a porosity of 52%. In the pharmaceutical industry, drug dissolution testing is routinely used to provide critical in vitro drug release information for both quality control purposes, i. The test relies on taking samples from the dissolution vessel during the dissolution process to obtain drug. the USPP, in coordination with its law enforcement partners, developed and executed its plan to clear the park and the USPP’s reasons for dispersing protesters from the area. According to FDA’s guidelines, a minimum value of 50 (50 < f 2 < 100) for similarity factor is required to ensure sameness or equivalence of two dissolution curves. Baskets with different wire openings can be used in alternative to the standard mesh opening (40-mesh) in order to discriminate between drug formulations during early stage of drug product development. pour suivre les résultats , voici le lien de la fédération:. DOI: 10. e. pour suivre les résultats , voici le lien de la fédération:. Uses Notes: Great in hanging baskets and patio planters. 2021. (c) Bottom of an empty basket. USP Basket - Saint Pierre de Bressieux, Saint-Pierre-de-Bressieux, France. Site Map. From my experiments about dissolution of Phenytoin Sodium Capsules by the USP dissolution apparatus I (basket type, 40 mesh), I found gelatinous subtance clogged at the bottom part of baket about 50% - 60% of area. The basket in the vessel acts as an impeller, although a very weak one. 2 μm PVDF 50/pk. It consisted of a 400-ml beaker and a three-blade, centrally placed polyethylene stirrer (5 cm diameter) rotated at 59 rpm in 250 ml of dissolution fluid (0. Perform a complete USP 1 method automatically from placement basket handling to a streamlined post-test cleaning routine. 31743682. E. On May 13, 2022, the USPP was finally able to provide a one page reply. 5,297 likes · 301 talking about this · 127 were here. The starches were evaluated in comparison with microcrystalline cellulose (MCC PH 101). US Pavilly. 8 Thus the Lord God showed me [a vision], and behold, there was a basket of [overripe] summer fruit. MCC forms matrix tablets and in the USP basket method the dissolution profiles followed square root of time kinetics indicating that diffusion was the rate-controlling step of ASA dissolution.